ABOUT LDN-27219 SIDE EFFECTS

EC dysfunction, characterised by blunted relaxations in response to acetylcholine and lowered NO bioavailability, was located in the aortas of male HAS-2 mice, while it had been unaltered within the aortas of feminine HAS-2 mice. Superoxide concentrations amplified and extracellular superoxide dismutase (ecSOD) expression reduced during the aortas